Description
t-Boc-aminooxy-PEG4-azide is a reagent designed for click chemistryfeaturing a t-Boc-aminooxy group. Its azide functionality can react with alkynes such as BCN or DBCO through click chemistry processes to yield stable triazole linkages. The protected aminooxy group can be deprotected under mild acidic conditions, and the hydrophilic PEG spacer increases solubility in aqueous environments.
Applications
In the field of drug discovery and development, this compound can be used to modify drug molecules. The t-Boc group offers protection during synthesis, and the aminooxy and azide functionalities allow for conjugation with other molecules to improve the pharmacokinetic and pharmacodynamic properties of the drug.