Description
t-boc-N-amido-PEG8-azide serves as a monodisperse PEG linker. The PEG8 spacer enhances solubility in aqueous environments. Its azide group can participate in reactions with alkynes, BCN, and DBCO via click chemistry techniques. Additionally, the Boc protecting group can be removed under mild acidic conditions to yield free amines.
Applications
In the area of peptide and protein modification, the t-boc protecting group can be selectively removed under specific conditions to expose the amine functionality for further reactions. In materials science, it can be incorporated into polymeric materials to control their properties such as hydrophobicity, mechanical strength, or surface functionality.