Amine/Azide/Methyltetrazine PEG reagent, N-(Azido-PEG1)-N-bis(PEG2-methyltetrazine-propylamine)

Synonym: Azido-PEG1-bis(PEG2-methyltetrazine-propylamine); N-(Azido-PEG1)-N-bis(2-(propylamino)-tetrazine-PEG2); N-(Azido-PEG1)-N-bis(PEG2-tetrazine-propylamine); N-(PEG1-Azido)-N-bis(PEG2-methyltetrazine)

Size

10 mg; 25 mg; 50 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-(Azido-PEG1)-N-bis(PEG2-methyltetrazine-propylamine) is a complex and multifunctional compound. It contains an azide group attached to a PEG1 chain, and two PEG2 chains each linked to a methyltetrazine and a propylamine moiety. The PEG chains contribute to improved solubility and biocompatibility. The azide group allows for specific conjugation reactions, while the methyltetrazine and propylamine components provide additional reactive and binding capabilities.

Molecular Weight

905

Molecular Formula

C₄₂H₆₀N₁₄O₉

Functional Group 1

Amine

Functional Group 2

Azide

Functional Group 3

Methyltetrazine

Reactive Group 1

Acid

Reactive Group 2

Alkyne

Form

Solid

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

N-(Azido-PEG1)-N-bis(PEG2-methyltetrazine-propylamine) is typically employed in bioorthogonal chemistry and targeted drug delivery. The azide and methyltetrazine groups allow for specific and rapid reactions, enabling precise conjugation of drugs or imaging agents to target biomolecules. It can be used to develop targeted therapeutics with enhanced efficacy and reduced side effects.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.