Amine/Azide/NHS PEG reagent, 2-(Azido-PEG3-amido)-1,3-bis(NHS ester), Purity 98%

Synonym: 2320560-36-7; 2-(Azido-PEG3-amido)-1,3-bis(NHS ester)

CAS Number: 2320560-36-7
PubChem CID: 138373724

Size

25 mg; 50 mg; 100 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) acts as a branched PEGylation agent where the presence of azide groups facilitates PEGylation through click chemistry methods. Its NHS ester functionality allows it to label primary amines found within proteins and amine-modified oligonucleotides among other amino-containing molecules while benefiting from enhanced hydrophilicity due to its PEG spacer

Molecular Weight

658.6

Molecular Formula

C₂₆H₃₈N₆O₁₄

Functional Group 1

NHS

Functional Group 2

Azide

Functional Group 3

Amine

Reactive Group 1

Alkyne

Reactive Group 2

Acid

Reactive Group 3

Amine

Form

Solid

Purity

98%

Solubility

DCM

Identity

Confirmed by NMR.

Applications

This compound is often used in bioconjugation processes. The NHS esters can react with amine groups on biomolecules such as proteins or peptides, while the azide-PEG moiety provides flexibility and solubility. It can be employed to attach labels, drugs, or other molecules to biomolecules for various applications like drug delivery and biomarker detection.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.