Amine/Azide/PNP PEG reagent, Azido-PEG8-Amido-Val-Cit-PAB-PNP, Purity 98%

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Cat. No.: X24-03-YW0504

Amine/Azide/PNP PEG reagent, Azido-PEG8-Amido-Val-Cit-PAB-PNP, Purity 98%

Synonym: Azido-PEG8-amido-Val-Cit-PAB-PNP; BP-29768

PubChem CID: 167312708

Size

50 mg; 100 mg; 250 mg; 500 mg

Price

Datasheet

MSDS

Properties

Description

Azido-PEG8-amido-Val-Cit-PAB-PNP is a reagent grade cleavable peptide ADC linker featuring an azido group, PEG8 spacer, and Val-Cit-PAB moiety.

Molecular Weight

1,081.2

Molecular Formula

C₄₇H₇₂N₁₀O₁₉

Functional Group 1

Amine

Functional Group 2

Azide

Functional Group 3

PNP

Reactive Group 1

Amine

Reactive Group 2

Alkyne

Form

Solid/liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Azido-PEG8-amido-Val-Cit-PAB-PNP is used in bioconjugation and targeted drug delivery research, facilitating Click Chemistry reactions with DBCO, BCN, or other alkyne groups, and enabling specific payload release by Cathepsin B cleavage, with the PNP group acting as a good leaving group.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

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