Amine/Biotin PEG reagent, Biotin-PEG23-amine, Purity 94%

Synonym: 604786-74-5; Biotin-PEG23-amine; NH₂-peg23-NH₂ Biotinamide; AKOS040743027

CAS Number: 604786-74-5
PubChem CID: 91757925

Size

100 mg; 250 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Biotin-PEG23-amine is a high molecular weight biotinylation reagent characterized by its long PEG spacer arm. This reagent is designed to react with carboxyl groups or 5' phosphate groups to form stable amide bonds. Its water solubility and extended PEG spacer contribute to enhanced solubility in aqueous media, facilitating efficient conjugation with biomolecules. Additionally, the PEG spacer helps mitigate steric hindrance, promoting effective binding to avidin molecules.

Molecular Weight

1,299.6

Molecular Formula

C₅₈H₁₁₄N₄O₂₅S

Functional Group 1

Amine

Functional Group 2

Biotin

Functional Group 3

None

Reactive Group 1

Carboxyl

Reactive Group 2

5'Phosphate

Form

Solid

Purity

94%

Identity

Confirmed by NMR.

Applications

Biotin-PEG23-amine is utilized in various biochemical and biotechnological applications requiring site-specific biotinylation of biomolecules. Its long PEG spacer arm enhances solubility and minimizes steric hindrance, making it suitable for labeling proteins, nucleic acids, and other macromolecules. This reagent finds applications in affinity purification, protein immobilization, and detection assays where biotin-streptavidin interactions play a crucial role.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.