Cat. No.: X24-03-YW0151
Amine/Biotin PEG reagent, Biotin-PEG23-amine, Purity 94%
Synonym: 604786-74-5; Biotin-PEG23-amine; NH2-peg23-NH2 Biotinamide; AKOS040743027
- CAS Number: 604786-74-5
- PubChem CID: 91757925
Size
100 mg; 250 mg; 500 mg
Properties
Description
Biotin-PEG23-amine is a high molecular weight biotinylation reagent characterized by its long PEG spacer arm. This reagent is designed to react with carboxyl groups or 5' phosphate groups to form stable amide bonds. Its water solubility and extended PEG spacer contribute to enhanced solubility in aqueous media, facilitating efficient conjugation with biomolecules. Additionally, the PEG spacer helps mitigate steric hindrance, promoting effective binding to avidin molecules.
Molecular Formula
C58H114N4O25S
Functional Group 2
Biotin
Reactive Group 1
Carboxyl
Reactive Group 2
5'Phosphate
Identity
Confirmed by NMR.
Applications
Biotin-PEG23-amine is utilized in various biochemical and biotechnological applications requiring site-specific biotinylation of biomolecules. Its long PEG spacer arm enhances solubility and minimizes steric hindrance, making it suitable for labeling proteins, nucleic acids, and other macromolecules. This reagent finds applications in affinity purification, protein immobilization, and detection assays where biotin-streptavidin interactions play a crucial role.
For Research Use Only. Not For
Clinical Use.