Cat. No.: X24-03-YW0153
Amine/Biotin PEG reagent, Biotin-PEG3-amine, Purity 98%
Synonym: 359860-27-8; Biotin-PEG3-amine; Amine-PEG3-biotin; N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE; (+)-biotin-PEG3-CH2CH2NH2
- CAS Number: 359860-27-8
- PubChem CID: 50896259
Size
100 mg; 250 mg; 500 mg; 1 g
Properties
Description
Biotin-PEG3-amine is a versatile biotinylation reagent suitable for conjugation with NHS esters or carboxylic acids in the presence of coupling agents like EDC or HATU. The PEG3 spacer enhances the aqueous solubility of the resulting biotin conjugates, while also reducing steric hindrance during binding to avidin molecules.
Molecular Formula
C18H34N4O5S
Functional Group 2
Biotin
Reactive Group 1
Carboxylic acid
Form
Solid (low melting point)
Identity
Confirmed by NMR.
Applications
Biotin-PEG3-amine is widely used in bioconjugation applications where the introduction of biotin functionality is required. Its reactivity with NHS esters and carboxylic acids allows for the facile modification of proteins, peptides, and other biomolecules with biotin tags. These biotinylated molecules can then be employed in various downstream applications including affinity purification, immunodetection, and protein labeling, benefiting from the enhanced solubility and reduced steric hindrance provided by the PEG3 spacer.
For Research Use Only. Not For
Clinical Use.