Amine/Biotin PEG reagent, Biotin-PEG3-amine, Purity 98%

Synonym: 359860-27-8; Biotin-PEG3-amine; Amine-PEG3-biotin; N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE; (+)-biotin-PEG3-CH₂CH₂NH₂

CAS Number: 359860-27-8
PubChem CID: 50896259

Size

100 mg; 250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Biotin-PEG3-amine is a versatile biotinylation reagent suitable for conjugation with NHS esters or carboxylic acids in the presence of coupling agents like EDC or HATU. The PEG3 spacer enhances the aqueous solubility of the resulting biotin conjugates, while also reducing steric hindrance during binding to avidin molecules.

Molecular Weight

418.6

Molecular Formula

C₁₈H₃₄N₄O₅S

Functional Group 1

Amine

Functional Group 2

Biotin

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

NHS

Form

Solid (low melting point)

Purity

98%

Identity

Confirmed by NMR.

Applications

Biotin-PEG3-amine is widely used in bioconjugation applications where the introduction of biotin functionality is required. Its reactivity with NHS esters and carboxylic acids allows for the facile modification of proteins, peptides, and other biomolecules with biotin tags. These biotinylated molecules can then be employed in various downstream applications including affinity purification, immunodetection, and protein labeling, benefiting from the enhanced solubility and reduced steric hindrance provided by the PEG3 spacer.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.