Amine/Biotin PEG reagent, Biotin-PEG4-amine, Purity 98%

Synonym: 663171-32-2; Biotin-PEG4-amine; (+)-Biotin-PEG4-CH₂CH₂NH₂; Biotin-PEG4-NH₂; N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

CAS Number: 663171-32-2
PubChem CID: 77078240

Size

100 mg; 250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Biotin-PEG4-amine is a widely used biotinylation reagent featuring a PEG spacer. It facilitates the formation of stable amide bonds when coupled to carboxyl groups or 5'phosphate groups. The PEG spacer enhances the aqueous solubility of molecules conjugated to biotin and reduces steric hindrance during binding to avidin molecules.

Molecular Weight

462.6

Molecular Formula

C₂₀H₃₈N₄O₆S

Functional Group 1

Amine

Functional Group 2

Biotin

Functional Group 3

None

Reactive Group 1

Carboxyl

Reactive Group 2

5'Phosphate

Form

Solid

Purity

98%

Solubility

Water, DCM, Ethanol

Identity

Confirmed by NMR.

Applications

Biotin-PEG4-amine is extensively utilized in bioconjugation studies, protein labeling, and biomolecule immobilization. Its amino group enables efficient coupling reactions with carboxyl groups or 5'phosphate groups, making it invaluable in various biochemical and biotechnological applications. Additionally, the PEG spacer enhances solubility and minimizes steric hindrance, optimizing the efficiency of biotin-avidin interactions.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.