Amine/Boc protecting PEG reagent, Bromoacetamido-PEG2-Boc-amine, Purity 98%

Synonym: 182244-33-3; Bromoacetamido-PEG2-Boc-amine; Bromoacetamido-C2-PEG2-NH-Boc; Tert-butyl (2-(2-(2-(2-bromoacetamido)ethoxy)ethoxy)ethyl)carbamate; Tert-butyl N-[2-[2-[2-[(2-bromoacetyl)amino]ethoxy]ethoxy]ethyl]carbamate

CAS Number: 182244-33-3
PubChem CID: 11046862

Size

250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bromoacetamido-PEG2-Boc-amine is a versatile PEG linker comprising a Boc-protected amine and a bromide group. The Boc protection ensures stability during synthesis, while the bromide group serves as an effective leaving group for nucleophilic substitution reactions. Additionally, the hydrophilic PEG spacer enhances solubility in aqueous environments.

Molecular Weight

369.3

Molecular Formula

C₁₃H₂₅BrN₂O₅

Functional Group 1

Amine

Functional Group 2

Boc protecting

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

NHS

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

Bromoacetamido-PEG2-Boc-amine is employed in various bioconjugation and chemical synthesis applications. The reactive amine group, upon deprotection under mild acidic conditions, enables conjugation with carboxylic acids, activated NHS esters, and other carbonyl compounds. Furthermore, the bromide group facilitates nucleophilic substitution reactions, allowing for the introduction of diverse functional groups.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.