Amine/Boc protecting PEG reagent, t-Boc-N-amido-PEG11-amine, Purity 98%

Synonym: 198227-38-2; t-Boc-N-amido-PEG11-amine; Boc-NH-PEG11-NH₂; t-Boc-N-amido-PEG12-amine

CAS Number: 198227-38-2
PubChem CID: 5079724

Size

250 mg; 500 mg; 1 g; 5 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

t-Boc-N-amido-PEG11-amine is a water-soluble polyethylene glycol (PEG) linker featuring an amino group and a tert-butoxycarbonyl (Boc)-protected amino group, connected by an eleven-unit PEG spacer. The hydrophilic nature of the PEG moiety enhances the solubility of the linker in aqueous environments, facilitating its application in aqueous-based reactions and formulations. The amino group serves as a versatile reactive site capable of participating in a variety of chemical reactions, including amidation with carboxylic acids, conjugation with activated NHS esters, and reductive amination with carbonyl-containing compounds such as ketones and aldehydes.

Molecular Weight

644.8

Molecular Formula

C₂₉H₆₀N₂O₁₃

Functional Group 1

Amine

Functional Group 2

Boc protecting

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

NHS

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

t-Boc-N-amido-PEG11-amine can be used in bioconjugation chemistry, drug delivery systems, and materials science applications. Its water solubility and reactive amino groups make it suitable for conjugation to biomolecules, polymers, or nanoparticles, enabling the preparation of PEGylated compounds with enhanced biocompatibility and pharmacokinetic profiles.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.