Cat. No.: X24-03-YW0277
Amine/Boc protecting PEG reagent, t-Boc-N-amido-PEG11-amine, Purity 98%
Synonym: 198227-38-2; t-Boc-N-amido-PEG11-amine; Boc-NH-PEG11-NH2; t-Boc-N-amido-PEG12-amine
- CAS Number: 198227-38-2
- PubChem CID: 5079724
Size
250 mg; 500 mg; 1 g; 5 g
Properties
Description
t-Boc-N-amido-PEG11-amine is a water-soluble polyethylene glycol (PEG) linker featuring an amino group and a tert-butoxycarbonyl (Boc)-protected amino group, connected by an eleven-unit PEG spacer. The hydrophilic nature of the PEG moiety enhances the solubility of the linker in aqueous environments, facilitating its application in aqueous-based reactions and formulations. The amino group serves as a versatile reactive site capable of participating in a variety of chemical reactions, including amidation with carboxylic acids, conjugation with activated NHS esters, and reductive amination with carbonyl-containing compounds such as ketones and aldehydes.
Molecular Formula
C29H60N2O13
Functional Group 2
Boc protecting
Reactive Group 1
Carboxylic acid
Identity
Confirmed by NMR.
Applications
t-Boc-N-amido-PEG11-amine can be used in bioconjugation chemistry, drug delivery systems, and materials science applications. Its water solubility and reactive amino groups make it suitable for conjugation to biomolecules, polymers, or nanoparticles, enabling the preparation of PEGylated compounds with enhanced biocompatibility and pharmacokinetic profiles.
For Research Use Only. Not For
Clinical Use.