Amine/Boc protecting PEG reagent, t-Boc-N-amido-PEG4-amine, Purity 98%

Synonym: 811442-84-9; Tert-Butyl (14-amino-3,6,9,12-tetraoxatetradecyl)carbamate; t-Boc-N-amido-PEG4-Amine; Boc-NH-PEG4-CH₂CH₂NH₂; BocNH-PEG4-CH₂CH₂NH₂

CAS Number: 811442-84-9
PubChem CID: 11688612

Size

250 mg; 500 mg; 1 g; 5 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

t-Boc-N-amido-PEG4-amine is a PEG linker featuring a Boc-protected amino group along with a four-unit PEG spacer. The Boc protection ensures stability during synthesis, while the free amino group remains available for conjugation reactions.

Molecular Weight

336.4

Molecular Formula

C₁₅H₃₂N₂O₆

Functional Group 1

Amine

Functional Group 2

Boc protecting

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

NHS

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

t-Boc-N-amido-PEG4-amine can be used in bioconjugation, drug delivery, and materials science applications. The free amino group is reactive with various functional groups including carboxylic acids, activated NHS esters, and carbonyls, enabling the synthesis of diverse bioconjugates. After deprotection of the Boc group under mild acidic conditions, the free amino group becomes available for further conjugation reactions or modifications, offering versatility in designing functionalized PEG-based compounds for specific research or industrial purposes.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.