Amine/Boc protecting PEG reagent, t-Boc-N-amido-PEG6-amine, Purity 98%

Synonym: 1091627-77-8; t-Boc-N-amido-PEG6-Amine; Boc-NH-PEG6-NH₂; Boc-NH-PEG6-amine; Boc-N-amido-PEG6-amine

CAS Number: 1091627-77-8
PubChem CID: 53401069

Size

250 mg; 500 mg; 1 g; 5 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

t-Boc-N-amido-PEG6-amine is a monodisperse PEG reagent featuring a tert-butoxycarbonyl (Boc) protecting group, an amide linkage, and a hydrophilic PEG spacer. The hydrophilic nature of the PEG spacer enhances the solubility of the compound in aqueous media, facilitating its use in aqueous-based reactions and formulations. The amino group remains reactive, allowing for conjugation with various functional groups such as carboxylic acids, activated NHS esters, and other reactive moieties.

Molecular Weight

424.5

Molecular Formula

C₁₉H₄₀N₂O₈

Functional Group 1

Amine

Functional Group 2

Boc protecting

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

NHS

Form

Liquid

Purity

98%

Solubility

Water, DMSO, DMF, DCM

Identity

Confirmed by NMR.

Applications

t-Boc-N-amido-PEG6-amine can be used as a building block in bioconjugation chemistry, peptide synthesis, and drug delivery. The presence of the Boc protecting group provides temporary protection for the amino functionality, allowing for selective functionalization of the PEG spacer. This reagent can be employed in the synthesis of PEGylated biomolecules, polymer conjugates, and peptide-based therapeutics. Its compatibility with aqueous environments makes it suitable for applications in biological assays, pharmaceutical formulations, and biomaterials science.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.