Amine/Boc protecting PEG reagent, t-Boc-N-amido-PEG9-amine, Purity 95%

Synonym: 890091-43-7; t-Boc-N-amido-PEG9-Amine; Boc-amido-PEG9-amine; BocNH-PEG9-CH₂CH₂NH₂; NHBoc-PEG9-amine

CAS Number: 890091-43-7
PubChem CID: 4641264

Size

250 mg; 500 mg; 1 g; 5 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

t-Boc-N-amido-PEG9-amine is a specialized PEG reagent comprising an amino group and a tert-butoxycarbonyl (Boc) protected amino group, joined by a nine-unit polyethylene glycol (PEG) spacer. The hydrophilic nature of the PEG segment enhances the solubility of the compound in aqueous solutions, facilitating its application in various biological and chemical contexts. The Boc protecting group can be selectively removed under mild acidic conditions, revealing the free amino functionality for subsequent conjugation reactions or derivatization steps.

Molecular Weight

556.7

Molecular Formula

C₂₅H₅₂N₂O₁₁

Functional Group 1

Amine

Functional Group 2

Boc protecting

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

NHS

Form

Liquid

Purity

95%

Solubility

Water, DMSO, DMF, DCM

Identity

Confirmed by NMR.

Applications

t-Boc-N-amido-PEG9-amine can be used as a versatile building block in the synthesis of PEGylated biomolecules, peptide conjugates, and polymeric materials. Its compatibility with aqueous environments makes it suitable for use in bioconjugation chemistry, drug delivery systems, and biomaterials engineering. Upon deprotection of the Boc group, the exposed amino group can participate in reactions with activated carboxylic acids, NHS esters, or other electrophilic species, enabling the efficient functionalization of the PEG spacer.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.