Amine/Carboxylic acid PEG reagent, t-Boc-N-amido-PEG24-acid, Purity 98%

Synonym: t-Boc-N-amido-PEG24-COOH; t-Boc-N-amido-PEG24-carboxylic acid; t-Boc-N-amido-polyethylene glycol 24-carboxylic acid; t-Boc-N-amido-PEG24-acetic acid

CAS Number: 187848-68-6

Size

250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

The t-Boc-N-amido-PEG24-acid is a PEG linker with a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in water-based solutions. The terminal carboxylic acid can form a stable amide bond with primary amine groups in the presence of activators (e.g. EDC, or HATU). The Boc group can be deprotected under mild acidic conditions to release the free amine. This product is reagent grade and intended for research purposes.

Molecular Weight

1246.5

Molecular Formula

C₅₆H₁₁₁NO₂₈

Functional Group 1

Acid

Functional Group 2

Amine

Functional Group 3

Boc

Reactive Group 1

Amine

Reactive Group 2

Acid

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

t-Boc-N-amido-PEG24-acid is commonly used in the synthesis of peptide-based therapeutics and in the modification of biomolecules to improve their stability and solubility.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.