Description
Sulfo DBCO-Amine is a reagent grade compound designed to derivatize carboxyl-containing molecules or activated esters with a DBCO moiety through a stable amide bond. Its low molecular weight adds minimal spacer to modified molecules, while the hydrophilic sulfonated spacer arm greatly improves the water solubility of DBCO-derivatized molecules.
Applications
Sulfo DBCO-Amine is used in bioconjugation and molecular biology research to efficiently modify carboxyl-containing molecules or activated esters with a DBCO moiety, enabling copper-free Click Chemistry reactions. Its sulfonated spacer arm enhances water solubility, making it ideal for modifying biomolecules and studying protein interactions.