Amine/Dibromo-Maleimide PEG reagent, 3,4-Dibromo-Mal-PEG8-Amine, Purity 95%

Synonym: 3,4-Dibromo-Mal-PEG8-Amine

PubChem CID: 165429918

Size

50 mg; 100 mg; 250 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

3,4-Dibromo-Mal-PEG8-Amine is a PEG linker featuring a site-specific amine group and a dibromomaleimide group. The dibromomaleimide moiety provides two reactive points, enabling dual substitution via the two bromine atoms. The amine group is highly reactive with carboxylic acids, activated NHS esters, carbonyl compounds, facilitating the formation of stable covalent bonds. The PEG spacer (8 ethylene glycol units) enhances water solubility, making this compound highly soluble in aqueous media.

Molecular Weight

650.4

Molecular Formula

C₂₂H₃₈Br₂N₂O₁₀

Functional Group 1

Amine

Functional Group 2

Dibromomaleimide

Reactive Group 1

Acid

Reactive Group 2

Thiol

Form

Solid

Purity

95%

Identity

Confirmed by NMR.

Applications

3,4-Dibromo-Mal-PEG8-Amine is primarily used in bioconjugation and drug delivery research. Its dual reactivity enables versatile functionalization, such as crosslinking biomolecules or attaching active compounds to proteins, antibodies, or other amine-modified entities. It is useful in the creation of custom drug carriers, antibody-drug conjugates (ADCs), and other research applications requiring stable and efficient conjugation.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.