Amine/DNP PEG reagent, DNP-PEG12-amine, Purity 95%

Synonym: Bifunctional PEG linker featuring a dinitrophenyl and a primary amine

Size

100 mg; 250 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DNP-PEG12-amine is a versatile PEG linker equipped with both a dinitrophenyl (DNP) moiety and a primary amine. The DNP component serves as an effective Förster resonance energy transfer (FRET) quencher, particularly when paired with tryptophan or tyrosine residues. Meanwhile, the primary amine offers flexibility for diverse applications, including reductive aminations and couplings, enabling the conjugation of various molecules or biomolecules.

Molecular Weight

754.8

Molecular Formula

C₃₂H₅₈N₄O₁₆

Functional Group 1

Amine

Functional Group 2

DNP

Functional Group 3

None

Reactive Group 1

Amine

Form

Reported

Purity

95%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

DNP-PEG12-amine can be used in fluorescence-based studies and bioconjugation strategies. The DNP moiety acts as an efficient quencher, facilitating fluorescence quenching in FRET-based assays when paired with suitable fluorophores. Moreover, the primary amine provides a reactive handle for conjugation with various molecules, allowing for the attachment of fluorescent probes, targeting ligands.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.