Amine/Fmoc-protected Amine/NHS PEG reagent, Fmoc-aminooxy-PEG12-NHS ester, Purity 98%

Synonym: 2765338-86-9; (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)oxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

CAS Number: 2765338-86-9

Size

50 mg; 100 mg; 250 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Fmoc-aminooxy-PEG12-NHS ester serves as a crosslinking agent where its NHS esters allow labeling of primary amines t-found within proteins or other molecules containing amino functionalities such as modified oligonucleotides. The hydrophilic nature of its PEG spacer also increases solubility when placed into aqueous media, and similarly, the Fmoc group can be deprotected under basic conditions yielding free aminogroups which may then participate in additional conjugations during research purposes.

Molecular Weight

953.1

Molecular Formula

C₄₆H₆₈N₂O₁₉

Functional Group 1

Amine

Functional Group 2

Fmoc

Functional Group 3

NHS

Reactive Group 1

Acid

Reactive Group 2

Amine

Form

Solid or viscous liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

This compound is utilized for the selective labeling of carbohydrates or glycoproteins through the oxime formation with aldehydes or ketones, enabling the study of glycosylation patterns in biological systems and the development of glyco-conjugates for therapeutic applications.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.