Properties
Description
N-Boc-PEG12-alcohol is a PEG linker featuring a terminal hydroxyl group and a Boc-protected amine. The PEG12 chain provides excellent hydrophilicity and solubility in aqueous media. The hydroxyl group offers reactivity for further functionalization, while the Boc group allows for acid-labile protection, enabling controlled amine activation.
Molecular Formula
C29H59NO14
Functional Group 2
Hydroxyl
Reactive Group 2
Nucleophile
Form
Liquid/Solid (low melting point)
Identity
Confirmed by NMR.
Applications
N-Boc-PEG12-alcohol is widely used in drug delivery, bioconjugation, and material synthesis. The hydroxyl group supports versatile chemical modifications, and the Boc group enables controlled deprotection for introducing free amines, making it ideal for designing hydrophilic linkers and tailored biomaterials.