Amine/t-Butyl ester PEG reagent, N-bis(Amine-PEG8)-N-(PEG8-t-butyl ester), Purity 98%

Synonym: BP-29791; N-bis(Amine-PEG8)-N-(PEG8-t-butyl ester)

PubChem CID: 167312699

Size

100 mg; 250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-bis(Amine-PEG8)-N-(PEG8-t-butyl ester) is a multifunctional 3-arm PEG linker characterized by a central t-butyl ester group flanked by two amino (NH₂) groups. The amino groups exhibit high reactivity towards activated NHS esters and carboxylic acids, facilitating bioconjugation and chemical modification processes. Additionally, the t-butyl protected carboxyl group offers stability during synthesis and can be selectively deprotected under acidic conditions, allowing for precise control over the reaction kinetics and enabling the subsequent functionalization of the exposed carboxyl moiety.

Molecular Weight

1,288.6

Molecular Formula

C₅₉H₁₂₁N₃O₂₆

Functional Group 1

Amine

Functional Group 2

t-Butyl ester

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

NHS

Form

Reported

Purity

98%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

N-bis(Amine-PEG8)-N-(PEG8-t-butyl ester) can be used in bioconjugation, drug delivery, and materials science applications. The amino groups serve as reactive handles for conjugating various biomolecules, therapeutic agents, and nanoparticles via- amide bond formation, enabling the synthesis of biofunctionalized materials with tailored properties. Moreover, the presence of the t-butyl ester moiety offers flexibility in the design of drug delivery systems and biomaterials, allowing for controlled release kinetics and enhanced stability during storage and transport.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.