Amine/t-Butyl ester PEG reagent, N-(t-butyl ester-PEG6)-N-bis(PEG6-amine), Purity 98%

Synonym: BP-29553; N-(t-butyl ester-PEG6)-N-bis(PEG6-amine)

PubChem CID: 167312775

Size

100 mg; 250 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-(t-butyl ester-PEG6)-N-bis(PEG6-amine) is a bifunctional PEG reagent featuring a central t-butyl ester group flanked by two PEG chains, each terminated with amine (NH₂) functional groups. The t-butyl ester serves as a protected carboxyl moiety, offering stability during synthesis and storage, while the amino groups provide sites for bioconjugation. The hydrophilic PEG spacers enhance the water solubility of the compound, facilitating its handling and application in aqueous media.

Molecular Weight

1,024.3

Molecular Formula

C₄₇H₉₇N₃O₂₀

Functional Group 1

Amine

Functional Group 2

t-Butyl ester

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

NHS

Form

Reported

Purity

98%

Identity

Confirmed by NMR.

Applications

N-(t-butyl ester-PEG6)-N-bis(PEG6-amine) can be used in bioconjugation, surface modification, and drug delivery applications. The amino groups enable the covalent attachment of various biomolecules, drugs, or nanoparticles via- amide bond formation, allowing for the synthesis of biofunctionalized materials with tailored properties. Additionally, the presence of the t-butyl ester moiety offers versatility in reaction conditions, allowing for controlled deprotection under mild acidic conditions, thereby facilitating precise control over the conjugation process.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.