Amine/Maleimide/t-Butyl ester/ PEG reagent, N-(Mal-PEG8-carbonyl)-N-bis(PEG8-t-butyl ester), Purity 98%

Synonym: Maleimide-PEG8-N-bis(PEG8-t-butyl ester); Mal-PEG8-N-bis(PEG8-t-butyl ester); Mal-PEG8-carbonyl-bis(PEG8-t-butyl ester)

Size

100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-(Mal-PEG8-carbonyl)-N-bis(PEG8-t-butyl ester) is a branched PEG linker featuring a maleimide group, a carbonyl functional group, and two t-butyl-protected esters. The maleimide group reacts selectively with thiol groups to form stable covalent bonds, while the t-butyl esters can be deprotected under acidic conditions to expose carboxylic acids. The PEG8 spacers enhance solubility and hydrophilicity in aqueous media.

Molecular Weight

1,552.9

Molecular Formula

C₇₂H₁₃₃N₃O₃₂

Functional Group 1

Amine

Functional Group 2

Maleimide

Functional Group 3

t-Butyl ester

Reactive Group 1

Acid

Reactive Group 2

Nucleophile

Reactive Group 3

Thiol

Form

Liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

N-(Mal-PEG8-carbonyl)-N-bis(PEG8-t-butyl ester) is employed in research for bioconjugation, crosslinking biomolecules, and developing advanced hydrophilic linkers. Its thiol-reactive maleimide group and acid-labile esters make it suitable for creating multifunctional biomaterials, studying thiol-specific modifications, and synthesizing macromolecular scaffolds in experimental studies.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.