Amine/NHS PEG reagent, t-Boc-Aminooxy-PEG12-NHS ester, Purity 96%

Synonym: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]oxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

Size

100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

t-Boc-Aminooxy-PEG12-NHS ester functions as a monodisperse PEG linker featuring both a t-Boc protected aminooxy group and an NHS ester moiety, allowing it to conjugate with amino-containing compounds effectively. Its hydrophilic PEG spacer increases solubility in water-based solutions, and the t-Boc group can be removed under mild acidic conditions.

Molecular Weight

830.9

Molecular Formula

C₃₆H₆₆N₂O₁₉

Functional Group 1

Boc

Functional Group 2

Amine

Functional Group 3

NHS

Reactive Group 1

Acid

Reactive Group 2

Amine

Form

Solid or viscous liquid

Purity

96%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

This compound can be used for selective labeling of glycoproteins or other biomolecules that have aldehyde groups. The aminooxy group can react with aldehydes, allowing for site-specific modifications, while the PEG segment improves water solubility.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.