Amine/NHS PEG reagent, t-Boc-N-amido-PEG2-CH₂CO₂-NHS ester, Purity 95%

Synonym: 911102-04-0; BocNH-PEG2-CH₂COONHS; 3,6,11-Trioxa-9-azatridecanoic acid, 12,12-dimethyl-10-oxo-, 2,5-dioxo-1-pyrrolidinyl ester; t-Boc-N-amido-PEG2-CH₂CO₂-NHS ester; (2,5-dioxopyrrolidin-1-yl) 2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]acetate

CAS Number: 911102-04-0
PubChem CID: 131750096

Size

100 mg; 250 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

t-Boc-N-amido-PEG2-CH₂CO₂-NHS ester serves as a PEG linker with both a terminal carboxylic acid and a Boc-protected amino group. The hydrophilic nature of the PEG spacer improves solubility in water. In the presence of activators such as EDC or HATU, the terminal carboxylic acid can react with primary amines to form stable amide bonds.

Molecular Weight

360.4

Molecular Formula

C₁₅H₂₄N₂O₈

Functional Group 1

Boc

Functional Group 2

Amine

Functional Group 3

NHS

Reactive Group 1

Acid

Reactive Group 2

Amine

Form

Solid or viscous liquid

Purity

95%

Identity

Confirmed by NMR.

Applications

This compound serves in the synthesis of peptide-drug conjugates. It is also used for modifying surfaces in biomedical applications to improve biocompatibility.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.

Amine/NHS PEG reagent, t-Boc-N-amido-PEG2-CH2CO2-NHS ester, Purity 95%

Amine/NHS PEG reagent, t-Boc-N-amido-PEG2-CH₂CO₂-NHS ester, Purity 95%