Amine/NHS PEG reagent, t-Boc-N-amido-PEG2-NHS ester, Purity 98%

Synonym: 2183440-73-3; t-Boc-N-amido-PEG2-NHS ester; Boc-NH-PEG2-C₂-NHS ester; 2,5-dioxopyrrolidin-1-yl 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatetradecan-14-oate; BocNH-PEG2-CH₂CH₂COONHS

CAS Number: 2183440-73-3
PubChem CID: 23591747

Size

100 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

t-Boc-N-amido-PEG2-NHS ester functions as another PEG linker featuring both an NHS ester and a t-Boc protected amino group. Its hydrophilic PEG spacer increases solubility when dissolved in aqueous media, and like before, the t-Boc group can be removed under mild acidic conditions to generate free amines suitable for various applications involving primary amines t-from proteins or modified oligonucleotides.

Molecular Weight

374.4

Molecular Formula

C₁₆H₂₆N₂O₈

Functional Group 1

Boc

Functional Group 2

Amine

Functional Group 3

NHS

Reactive Group 1

Acid

Reactive Group 2

Amine

Form

Solid or viscous liquid

Purity

98%

Solubility

DCM

Identity

Confirmed by NMR.

Applications

This compound serves similar functions in peptide synthesis and bioconjugation as the PEG3 variant but with an optimized spacer length that may influence the flexibility and solubility of the final conjugate, enhancing its pharmacokinetic properties.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.