Amine/NHS PEG reagent, t-Boc-N-amido-PEG3-NHS ester, Purity 98%

Synonym: 2250216-93-2; Boc-NH-PEG3-NHS ester; t-Boc-N-amido-PEG3-NHS ester; BocNH-PEG3-CH₂COONHS; 2,5-Dioxopyrrolidin-1-yl 2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azaheptadecan-17-oate

CAS Number: 2250216-93-2
PubChem CID: 134827758

Size

250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

t-Boc-N-amido-PEG3-NHS ester is a PEG linker that features an NHS ester and a t-Boc protected amine group. The hydrophilic PEG spacer enhances the solubility of compounds in aqueous solutions. Under mild acidic conditions, the t-Boc group can be removed to yield free amines. This NHS ester is suitable for labeling primary amines t-found in proteins, amine-modified oligonucleotides, and other molecules containing amino groups.

Molecular Weight

418.4

Molecular Formula

C₁₈H₃₀N₂O₉

Functional Group 1

Boc

Functional Group 2

Amine

Functional Group 3

NHS

Reactive Group 1

Acid

Reactive Group 2

Amine

Form

Solid or viscous liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

This compound is often used in peptide synthesis and as a linker for bioconjugation applications. Its NHS ester functionality allows for covalent attachment to amine-containing molecules, making it useful in drug delivery systems and the development of biopharmaceuticals.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.