Amine/NHS PEG reagent, t-Boc-N-amido-PEG5-NHS ester, Purity 98%

Synonym: 2055040-78-1; t-Boc-N-amido-PEG5-NHS ester; Boc-N-PEG5-C₂-NHS ester; t-BOC-N-amido-PEG5-NHSESTER; 2,5-dioxopyrrolidin-1-yl 2,2-dimethyl-4-oxo-3,8,11,14,17,20-hexaoxa-5-azatricosan-23-oate

CAS Number: 2055040-78-1
PubChem CID: 119058276

Size

250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

t-Boc-N-amido-PEG5-NHS ester functions as a PEG linker featuring an NHS ester and a Boc-protected amino group. The hydrophilic nature of its PEG spacer enhances solubility in aqueous solutions. Under mild acidic conditions, the Boc group can be removed to yield free amines. This NHS ester is suitable for labeling primary amines t-present in proteins, amine-modified oligonucleotides, and other molecules containing amino groups.

Molecular Weight

506.6

Molecular Formula

C₂₂H₃₈N₂O₁₁

Functional Group 1

Boc

Functional Group 2

Amine

Functional Group 3

NHS

Reactive Group 1

Acid

Reactive Group 2

Amine

Form

Solid or viscous liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

t-Boc-N-amido-PEG5-NHS ester is commonly employed in the synthesis and modification of peptides and proteins to add PEG moieties for improved properties.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.