Description
Thalidomide-PEG4-NH2 HCl salt is a a PROTAC linker with a thalidomide, a PEG spacer, and a primary amine that is used for medicinal purposes. PEG4-NH2 is a polyethylene glycol derivative that alters the properties of a drug, thereby improving its efficacy.
Applications
Thalidomide-PEG4-NH22 HCl salt is a useful tool in biomedical fields, is used for further derivatization through a variety of reactions. Thalidomide is a ligand for E3 ligase, which ubiquitinylates proteins for subsequent proteolysis.