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Amine/Thalidomide PEG reagent, Thalidomide-PEG4-NH2, HCl salt, Purity 95%
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Amino PEG
Amino-PEG10-acid (Cat#: X24-03-YW0001) N-(Mal-PEG6)-N-bis(PEG3-amine) (Cat#: X24-03-YW0002) Amino-PEG23-amine (Cat#: X24-03-YW0056) Amino-PEG20-t-butyl ester (Cat#: X24-03-YW0057) Amino-PEG1-amine (Cat#: X24-03-YW0058) Gly-PEG3-amine TFA salt (Cat#: X24-03-YW0064) Amino-PEG9-amine (Cat#: X24-03-YW0068) Amino-PEG8-amine (Cat#: X24-03-YW0072) Amino-PEG8-t-butyl ester (Cat#: X24-03-YW0087)
Biotin PEG
Biotin-PEG2-azide (Cat#: X24-03-YW0091) Biotin-PEG5-azide (Cat#: X24-03-YW0113) Biotin-PEG6-t-butyl ester (Cat#: X24-03-YW0114) Dde biotin azide plus (Cat#: X24-03-YW0115) Biotin-PEG2-NH-Boc (Cat#: X24-03-YW0116) Biotin-PEG11-amine (Cat#: X24-03-YW0117) Biotin-PEG4-amide (Cat#: X24-03-YW0118) Biotin-PEG4-azide (Cat#: X24-03-YW0119) Biotin-PEG12-NHS ester (Cat#: X24-03-YW0124)
DBCO PEG
DBCO-PEG5-TFP ester (Cat#: X24-03-YW0294) DBCO-C3-alcohol (Cat#: X24-03-YW0306) Hydroxy-PEG7-DBCO (Cat#: X24-03-YW0307) DBCO-C5-acid (Cat#: X24-03-YW0308) DBCO-PEG2-amine (Cat#: X24-03-YW0310) DBCO STP ester (Cat#: X24-03-YW0311) DBCO-PEG6-DBCO (Cat#: X24-03-YW0312)
Poly PEG
m-PEG-succinic acid (Cat#: X24-10-WXX03) Lipoamide-PEG-Mal (Cat#: X24-10-WXX05) m-PEG-SPDP (Cat#: X24-10-WXX06) Lipoamide-PEG-biotin (Cat#: X24-10-WXX07) Rhodamine-PEG-Mal (Cat#: X24-10-WXX08) Cholesterol-PEG-methoxy (Cat#: X24-10-WXX10) DSPE-PEG-Ald (Cat#: X24-10-WXX12) 4-Arm PEG-OH (Cat#: X24-10-WXX13)
PEG Acid
m-PEG4-(CH2)3-acid (Cat#: X24-09-YYX001) m-PEG9-acid (Cat#: X24-09-YYX005) m-PEG1-acid (Cat#: X24-09-YYX008) Biotin-PEG2-acid (Cat#: X24-09-YYX011) Acid-PEG4-t-butyl ester (Cat#: X24-09-YYX015) Amino-PEG3-acid (Cat#: X24-09-YYX018) m-PEG11-CH2CO2H (Cat#: X24-09-YYX020) Amino-PEG4-CH2CO2H (Cat#: X24-09-YYX022)
PEG Azide
t-boc-N-amido-PEG5-azide (Cat#: X24-09-YYX148) Aminooxy-PEG4-azide (Cat#: X24-09-YYX246) AZD-PEG2-azide (Cat#: X24-09-YYX248) Azido-PEG12-azide (Cat#: X24-09-YYX249) Trityl-PEG10-azide (Cat#: X24-09-YYX250) Bromoacetamido-PEG2-azide (Cat#: X24-09-YYX251) Azido-PEG24-alcohol (Cat#: X24-09-YYX255) m-PEG6-azide (Cat#: X24-09-YYX257)
Bromo PEG
Bromo-PEG2-methyl ester (Cat#: X24-03-YW0205) Bromoacetamido-PEG8-acid (Cat#: X24-03-YW0209) Bromoacetamido-PEG3-acid (Cat#: X24-03-YW0213) Amino-PEG8-Bromo (Cat#: X24-03-YW0215) Bis-bromoacetamido-PEG11 (Cat#: X24-03-YW0216) Bromoacetamido-PEG8-t-butyl ester (Cat#: X24-03-YW0218) Bromo-PEG1-CH2CO2-t-Bu (Cat#: X24-03-YW0220)


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Cat. No.: X24-10-WXX489

Amine/Thalidomide PEG reagent, Thalidomide-PEG4-NH2, HCl salt, Purity 95%

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Synonym: Thalidomide 4'-ether-PEG3-amine; 2387510-82-7; Thalidomide-PEG4-NH2 (hydrochloride); Thalidomide-PEG4-NH2 hydrochloride; Thalidomide-linker 11

  • CAS Number: 2387510-82-7
  • PubChem CID: 146018962
Size
25 mg; 50 mg; 100 mg
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Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Thalidomide-PEG4-NH2 HCl salt is a a PROTAC linker with a thalidomide, a PEG spacer, and a primary amine that is used for medicinal purposes. PEG4-NH2 is a polyethylene glycol derivative that alters the properties of a drug, thereby improving its efficacy.
Molecular Weight
449.5
Molecular Formula
C21H27N3O8
Functional Group 1
Amine
Functional Group 2
Thalidomide
Functional Group 3
None
Reactive Group 1
Acid
Form
Solid
Purity
95%
Identity
Confirmed by NMR.
Applications
Thalidomide-PEG4-NH22 HCl salt is a useful tool in biomedical fields, is used for further derivatization through a variety of reactions. Thalidomide is a ligand for E3 ligase, which ubiquitinylates proteins for subsequent proteolysis.
Storage
Store at -20°C.
For Research Use Only. Not For Clinical Use.
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