Description
Tri(amino-PEG5-amide)-amine is a water-soluble PEG linker designed for versatile bioconjugation applications. Featuring three amino groups along with a PEG5 spacer, this linker offers enhanced solubility in aqueous environments. The amino groups are highly reactive and can readily participate in conjugation reactions with various functional groups, including carboxylic acids, activated NHS esters, and carbonyls such as ketones and aldehydes.
Applications
Tri(amino-PEG5-amide)-amine serves as a valuable tool in bioconjugation chemistry, enabling the coupling of diverse molecules for biomedical research and therapeutic applications. Its water solubility and versatile reactivity make it suitable for a wide range of conjugation strategies, including the attachment of peptides, proteins, antibodies, and small molecules to surfaces, polymers, nanoparticles, and other biomolecules. The availability of multiple amino groups facilitates the generation of multifunctional conjugates with controlled stoichiometry and spatial orientation, making it an essential component in the development of targeted drug delivery systems, diagnostic probes, and biomaterials for tissue engineering.