Amino/Bromide PEG reagent, N-Boc-PEG23-bromide, Purity 95%

Synonym: 2252157-01-8; N-Boc-PEG23-bromide; AKOS040743653; BP-25005; HY-141197; CS-0114973

CAS Number: 2252157-01-8
PubChem CID: 134811395

Size

10 mg; 50 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-Boc-PEG23-bromide is a PEG linker compound characterized by the presence of a bromide group and a tert-butoxycarbonyl (Boc)-protected amino group. This molecule features a polyethylene glycol (PEG) spacer, which enhances its solubility in aqueous environments. The bromide (Br) serves as an effective leaving group, facilitating nucleophilic substitution reactions. Additionally, the Boc protecting group shields the amino functionality, preventing unwanted reactions during synthetic transformations. Under mild acidic conditions, the Boc group can be selectively removed, revealing the free amino group for further chemical modifications or conjugation reactions.

Molecular Weight

1,237.3

Molecular Formula

C₅₃H₁₀₆BrNO₂₅

Functional Group 1

Amino

Functional Group 2

Bromide

Functional Group 3

None

Form

Solid (low melting point)

Purity

95%

Solubility

DCM

Identity

Confirmed by NMR.

Applications

N-Boc-PEG23-bromide can be used as a versatile building block in organic synthesis and chemical conjugation strategies. The hydrophilic nature of the PEG spacer imparts water solubility to the compound, making it suitable for aqueous-based reactions and biological applications. The bromide moiety enables facile substitution reactions, allowing for the introduction of diverse functional groups or biomolecules onto the PEG backbone. Moreover, the Boc protecting group ensures the stability of the amino functionality during synthetic steps, preventing premature reactions.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.