Cat. No.: X24-03-YW0270
Amino/Bromide PEG reagent, N-Boc-PEG3-bromide, Purity 98%
Synonym: 1076199-21-7; N-Boc-PEG3-bromide; 1-Boc-amino-3,6,9-trioxaundecanyl-11-bromide; Tert-Butyl (2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)ethyl)carbamate; Tert-butyl N-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethyl]carbamate
- CAS Number: 1076199-21-7
- PubChem CID: 29974540
Size
250 mg; 500 mg; 1 g; 5 g
Properties
Description
N-Boc-PEG3-bromide is a PEG linker compound featuring a tert-butoxycarbonyl (Boc)-protected amine and a bromide group. The Boc protecting group shields the amino functionality from unwanted reactions and can be selectively removed under mild acidic conditions. The presence of the bromide (Br) moiety imparts reactivity to the molecule, as it serves as an excellent leaving group for nucleophilic substitution reactions. This characteristic makes N-Boc-PEG3-bromide suitable for various synthetic transformations and conjugation reactions.
Molecular Formula
C13H26BrNO5
Functional Group 2
Bromide
Solubility
DMSO, DCM, DMF
Identity
Confirmed by NMR.
Applications
N-Boc-PEG3-bromide can be used as a versatile building block in organic synthesis and chemical conjugation strategies. The Boc protecting group ensures the stability of the amine functionality during synthetic steps, allowing for controlled deprotection when desired. The bromide group enables facile substitution reactions, facilitating the introduction of diverse functional groups or biomolecules onto the PEG backbone. This compound can be utilized in the synthesis of tailored PEG-based conjugates or bioconjugates for applications in drug delivery, diagnostics, and materials science.
For Research Use Only. Not For
Clinical Use.