Amino/Bromide PEG reagent, N-Boc-PEG3-bromide, Purity 98%

Synonym: 1076199-21-7; N-Boc-PEG3-bromide; 1-Boc-amino-3,6,9-trioxaundecanyl-11-bromide; Tert-Butyl (2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)ethyl)carbamate; Tert-butyl N-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethyl]carbamate

CAS Number: 1076199-21-7
PubChem CID: 29974540

Size

250 mg; 500 mg; 1 g; 5 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-Boc-PEG3-bromide is a PEG linker compound featuring a tert-butoxycarbonyl (Boc)-protected amine and a bromide group. The Boc protecting group shields the amino functionality from unwanted reactions and can be selectively removed under mild acidic conditions. The presence of the bromide (Br) moiety imparts reactivity to the molecule, as it serves as an excellent leaving group for nucleophilic substitution reactions. This characteristic makes N-Boc-PEG3-bromide suitable for various synthetic transformations and conjugation reactions.

Molecular Weight

356.3

Molecular Formula

C₁₃H₂₆BrNO₅

Functional Group 1

Amino

Functional Group 2

Bromide

Functional Group 3

None

Form

Liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

N-Boc-PEG3-bromide can be used as a versatile building block in organic synthesis and chemical conjugation strategies. The Boc protecting group ensures the stability of the amine functionality during synthetic steps, allowing for controlled deprotection when desired. The bromide group enables facile substitution reactions, facilitating the introduction of diverse functional groups or biomolecules onto the PEG backbone. This compound can be utilized in the synthesis of tailored PEG-based conjugates or bioconjugates for applications in drug delivery, diagnostics, and materials science.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.