Applications
t-Boc-aminooxy-PEG5-amine is indispensable in bioconjugation chemistry, facilitating specific coupling reactions with carboxylic acids and activated NHS esters. After deprotection under mild acidic conditions, the aminooxy group reacts with aldehydes or ketones to form stable oxime linkages. Its hydrophilic PEG spacer enhances solubility in aqueous media, making it suitable for a wide range of applications, including protein labeling, drug delivery, and biomaterials research.