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Aminooxy/Bu PEG reagent, t-Boc-aminooxy-PEG4-CH2CO2-t-Bu, Purity 97%
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Cat. No.: X24-03-YW0029

Aminooxy/Bu PEG reagent, t-Boc-aminooxy-PEG4-CH2CO2-t-Bu, Purity 97%

Synonym: 2062663-63-0; t-Boc-aminooxy-PEG4-CH2CO2-t-Bu; Boc-aminooxy-PEG4-CH2-Boc

  • CAS Number: 2062663-63-0
  • PubChem CID: 126480495
Size
500 mg
Price
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Datasheet
Datasheet
MSDS
MSDS
Properties
Description
t-Boc-aminooxy-PEG4-CH2CO2-t-Bu is a PEG linker featuring a t-Boc protected aminooxy group and a t-Bu carboxylic acid group. The protected aminooxy can be deprotected under mild acidic conditions for coupling with aldehyde or ketone groups, forming stable oxime linkages. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG linker enhances water solubility.
Molecular Weight
423.5
Molecular Formula
C19H37NO9
Functional Group 1
Aminooxy
Functional Group 2
Bu
Functional Group 3
None
Reactive Group 1
Carbonyl
Form
Reported
Purity
97%
Identity
Confirmed by NMR.
Applications
t-Boc-aminooxy-PEG4-CH2CO2-t-Bu is essential in bioconjugation, enabling specific coupling reactions with aldehyde or ketone groups. After deprotection, the aminooxy group forms stable oxime bonds, allowing for precise modification of biomolecules. Its hydrophilic PEG linker ensures compatibility with aqueous environments, making it suitable for various applications such as protein labeling, drug delivery, and biomaterials development.
Storage
Store at -20°C
For Research Use Only. Not For Clinical Use.
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