Amino/Propargyl PEG reagent, N-(Amine-PEG3)-N-bis-(PEG3-amino-tri-(propargyl-PEG2-ethoxymethyl)-methane), TFA salt, Purity 98%

Synonym: BP-29213

PubChem CID: 167312828

Size

50 mg; 100 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-(Amine-PEG3)-N-bis-(PEG3-amino-tri-(propargyl-PEG2-ethoxymethyl)-methane), TFA salt is a complex PEGylation reagent featuring a branched structure with an amino group and six propargyl groups. The amino group facilitates conjugation with carboxylic acids and activated NHS esters, while the propargyl groups enable participation in copper-catalyzed Click Chemistry reactions.

Molecular Weight

1,990.4

Molecular Formula

C₉₄H₁₆₀N₁₀O₃₅

Functional Group 1

Amino

Functional Group 2

Propargyl

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

NHS

Form

Liquid/Solid (low melting point)

Purity

98%

Identity

Confirmed by NMR.

Applications

N-(Amine-PEG3)-N-bis-(PEG3-amino-tri-(propargyl-PEG2-ethoxymethyl)-methane), TFA salt can be used utilized in bioconjugation applications where precise and efficient labeling or modification of biomolecules is required. The amino groups can be selectively coupled with carboxyl groups of biomolecules or activated NHS esters to form stable amide bonds, facilitating the attachment of PEG chains. Additionally, the presence of propargyl groups enables further functionalization via- copper-catalyzed Click Chemistry, allowing for the conjugation of various molecules, including fluorescent dyes, targeting ligands, or other bioactive moieties.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.