APN PEG reagent, APN-C3-PEG5-acid, Purity 98%

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Cat. No.: X24-03-YW0003

APN PEG reagent, APN-C3-PEG5-acid, Purity 98%

Synonym: PEG-based PROTAC linker

Size

10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

APN-C3-PEG5-acid is a novel thiol-specific conjugation reagent featuring a stable thiol-reactive 3-arylpropiolonitrile (APN) group. It exhibits excellent stability in aqueous environments, facilitating targeted coupling of thiols in biomolecules.

Molecular Weight

547.6

Molecular Formula

C₂₇H₃₇N₃O₉

Functional Group 1

APN

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Thiol

Form

Liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

APN-C3-PEG5-acid is essential for specific and stable conjugation of thiols in biomolecules without the risk of side reactions associated with maleimides. It finds wide application in bioconjugation chemistry, enabling precise modification of proteins, peptides, and other biomolecules for various research purposes, including drug delivery, diagnostics, and biotechnology.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.

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