Description
APN-C3-PEG5-acid is a novel thiol-specific conjugation reagent featuring a stable thiol-reactive 3-arylpropiolonitrile (APN) group. It exhibits excellent stability in aqueous environments, facilitating targeted coupling of thiols in biomolecules.
Applications
APN-C3-PEG5-acid is essential for specific and stable conjugation of thiols in biomolecules without the risk of side reactions associated with maleimides. It finds wide application in bioconjugation chemistry, enabling precise modification of proteins, peptides, and other biomolecules for various research purposes, including drug delivery, diagnostics, and biotechnology.