AZD PEG reagent, AZD-PEG2-PFP, Purity 98%

Synonym: 1807537-41-2; Azd-peg2-pfp; AZD-PEG2 -PFP; DTXSID601101952; BP-22033

CAS Number: 1807537-41-2
PubChem CID: 77078270

Size

100 mg; 250 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD-PEG2-PFP is a PEG linker comprising an AZD (azido) group and a PFP (pentafluorophenyl) ester group. The PFP ester serves as an activated ester capable of reacting with primary amines to establish amide bonds. Renowned for its stability, the PFP ester exhibits a reduced susceptibility to hydrolysis compared to other amine-reactive groups, ensuring reliable and efficient conjugation reactions with primary amine-containing molecules.

Molecular Weight

572.5

Molecular Formula

C₂₆H₂₅F₅N₂O₇

Functional Group 1

AZD

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Amine

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

AZD-PEG2-PFP can be used in diverse bioconjugation applications, primarily in the modification of biomolecules possessing primary amine functionalities. Through its reaction with primary amines, the PFP ester facilitates the conjugation of the AZD-PEG2 linker to proteins, peptides, antibodies, and other amine-containing molecules. Such conjugation reactions enable the development of bioconjugates utilized in various biomedical and biotechnological fields.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.