Description
14-(Azide-PEG3-ethylcarbamoyl)tridecanoic-t-butyl ester features an azide group attached to a PEG linker with an alkane tail that terminates in a t-butyl ester. The azide moiety can react with alkyne compounds, BCN, and DBCO through click chemistry methods to form stable triazole linkages. Additionally, the t-butyl protected carboxylic acid can be deprotected under acidic conditions. This compound is a self-assembling PEG reagent capable of forming micelles in aqueous environments and may serve as a building block for lipids in nanotechnology and drug delivery applications.
Applications
In the synthesis of lipid-based nanoparticles for drug delivery, 14-(Azide-PEG3-ethylcarbamoyl)tridecanoic-t-butyl ester can help control the size, shape, and surface properties of the particles. It can also be used in the development of self-assembled monolayers on surfaces for biosensing applications. Moreover, it can be incorporated into polymers to impart specific functionalities such as improved solubility and biocompatibility.