Description
18-(Azide-PEG3-ethylcarbamoyl)heptadecanoic-t-butyl ester is a PEG linker that features an azide group along with an alkane tail terminating in a t-butyl ester. The azide moiety can react with alkyne compounds, BCN, and DBCO through click chemistry methods to form stable triazole linkages. Additionally, the t-butyl protected carboxylic acid can be deprotected under acidic conditions. This polymer has the ability to spontaneously form micelles in aqueous environments and may also be utilized for synthesizing more complex lipids suitable for drug delivery nanoparticles.