Azide PEG reagent, 5-(Azide-PEG9-ethylcarbamoyl)pentanoic t-butyl ester, Purity 98%

Synonym: 5-Azido-PEG9-ethylcarbamoyl pentanoic acid t-butyl ester; t-butyl ester of 5-(Azide-PEG9-ethylcarbamoyl)pentanoic acid; Azide-PEG9-ethylcarbamoyl-5-pentanoic t-butyl ester

Size

50 mg; 100 mg; 250 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

5-(Azide-PEG9-ethylcarbamoyl)pentanoic t-butyl ester is a PEG compound that features both an azide group and a t-butyl ester moiety. The azide (N3) can engage in reactions with alkynes, BCN, and DBCO through click chemistry methods to form stable triazole linkages. Furthermore, the carboxylic acid protected by t-butyl can be deprotected under acidic conditions.

Molecular Weight

666.8

Molecular Formula

C₃₀H₅₈N₄O₁₂

Functional Group 1

Azide

Functional Group 2

t-Butyl ester

Functional Group 3

Ether

Reactive Group 1

Alkynyl

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

This compound is applicable in lipid modification and the design of lipid-based drug delivery systems. The azide group provides a site for conjugation with other molecules for targeted delivery or functionalization. The PEG9 chain improves the solubility and biocompatibility of the lipid molecule. The t-butyl ester can be selectively deprotected to expose the carboxylic acid group for further chemical modifications. This enables the formulation of lipid nanoparticles or liposomes with enhanced drug loading and targeting efficiency.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.