Azide PEG reagent, 6-Azido-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)hexanamide, Purity 95%

Synonym: 2227423-33-6; 6-Azido-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)hexanamide; 6-azido-N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]hexanamide; SCHEMBL20573342; AKOS037654827

CAS Number: 2227423-33-6
PubChem CID: 135389847

Size

25 mg; 50 mg; 100 mg; 250 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

6-Azido-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)hexanamide is a reagent grade PROTAC linker featuring a pomalidomide, an aliphatic spacer, and an azide. Pomalidomide recruits E3 ligase for the ubiquitinylation and subsequent proteolysis of target proteins.

Molecular Weight

412.4

Molecular Formula

C₁₉H₂₀N₆O₅

Functional Group 1

Azide

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Alkyne

Form

Solid

Purity

95%

Identity

Confirmed by NMR.

Applications

6-Azido-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)hexanamide is used in molecular biology and bioconjugation research by click chemistry. Pomalidomide recruits E3 ligase for the ubiquitination and subsequent proteolysis of target proteins.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.