Azide PEG reagent, Azido-PEG12-t-butyl ester, Purity 98%

Synonym: Azido-PEG12-Boc; tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

CAS Number: 1818294-45-9

Size

100 mg; 250 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-PEG12-t-butyl ester is a PEG linker that is soluble in water. The azide (N3) group can react with alkynes, such as BCN and DBCO, through click chemistry to form stable triazole linkages.

Molecular Weight

699.8

Molecular Formula

C₃₁H₆₁N₃O₁₄

Functional Group 1

Azide

Functional Group 2

t-Butyl ester

Functional Group 3

None

Reactive Group 1

Alkynyl

Form

Solid

Purity

98%

Solubility

Water, DMSO, DMF, DCM

Identity

Confirmed by NMR.

Applications

It can be incorporated into liposomes or micelles to enhance the circulation time of the drug payload and increase its accumulation at the target site. Moreover, it can be used in the synthesis of polymeric nanoparticles for controlled drug release. In materials science, it can be used to modify the surface properties of materials, making them more biocompatible and suitable for biomedical applications.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.