Azide PEG reagent, Azido-PEG6-t-butyl ester, Purity 98%

Synonym: 406213-76-1; AZIDO-PEG6-t-butyl ESTER; N₃-PEG6-tBu; Azido-PEG6-C₂-Boc; N₃-PEG6- CH2CH2COOtBu

CAS Number: 406213-76-1
PubChem CID: 60146167

Size

100 mg; 500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-PEG6-t-butyl ester consists of a PEG molecule that includes both an azide group and a t-butyl ester functionality. Similar to previous products mentioned, this azide can engage in reactions with alkyne compounds like BCN or DBCO through click chemistry processes resulting in stable triazole formations. Furthermore, the t-butyl protected carboxylic acid can be deprotected under acidic conditions, and the hydrophilic nature of the PEG5 spacer improves solubility in water-based media.

Molecular Weight

435.5

Molecular Formula

C₁₉H₃₇N₃O₈

Functional Group 1

Azide

Functional Group 2

t-Butyl ester

Functional Group 3

None

Reactive Group 1

Alkynyl

Form

Solid

Purity

98%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Azido-PEG6-t-butyl ester can be employed in drug delivery systems to modify drug molecules and improve their solubility and pharmacokinetic properties. The t-butyl ester can be selectively removed to expose reactive groups.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.