Description
Azido-PEG8-PFP ester acts as a monodisperse PEG linker featuring both an azide functionality and PFP ester groups. This azide participates in click chemistry reactions involving alkynes such as DBCO or BCN to create triazole structures. Moreover, the PFP ester exhibits reactivity towards amines while being less prone to hydrolysis compared to NHS esters.
Applications
In the area of bioconjugation, the azide group allows for specific and efficient click chemistry reactions, enabling the attachment of biomolecules such as proteins, antibodies, or nucleic acids.