Description
Bromo-PEG6-azide features a bromide (Br), a terminal azide (N3), and a PEG6 spacer. The PEG spacer enhances solubility in aqueous solutions. The bromine atom serves as an effective leaving group for nucleophilic substitution reactions. Additionally, the azide can react with alkynes, BCN, and DBCO through click chemistry to form stable triazole linkages.
Applications
Bromo-PEG6-azide can be used in sequential chemical reactions for the synthesis of diverse molecules. The bromo group and the azide group provide different reactive sites for conjugation and functionalization, making it useful in the preparation of complex biomolecular conjugates or materials.