Description
Iodo-PEG3-azide serves as a PEG linker incorporating both iodide and azide functionalities. The hydrophilic nature of the PEG spacer enhances solubility in aqueous solutions. Its azide group can engage in reactions with alkynes, BCN, or DBCO via- click chemistry to yield stable triazole linkages. Furthermore, the iodide acts as an excellent leaving group for nucleophilic substitution reactions.
Applications
In the field of bioconjugation, it can be used to attach biomolecules such as proteins or peptides. The azide group enables click chemistry reactions, and the iodo functionality offers additional reactivity options.