Description
Iodoacetamide azide consists of an azide moiety paired with a terminal iodide group. The azide can engage in reactions with alkyne compounds like BCN or DBCO through click chemistry methods resulting in stable triazole formations. Additionally, the iodoacetamide portion acts as an alkylating agent capable of covalently binding to thiol groups.
Applications
In drug discovery, it can be used to identify and characterize protein targets and to develop targeted therapeutics. It can also be applied in the development of affinity chromatography resins for protein purification.