Azide/Amine/Carboxylic acid PEG reagent, N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid, Purity 98%

Synonym: 2183440-70-0; Azide PEG reagent; Iodoacetamido-PEG6-azide

CAS Number: 2183440-70-0
PubChem CID: 132451883

Size

50 mg; 100 mg; 250 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid serves as a heterotrifunctional PEG linker incorporating azide (N3), amine (NH2), and carboxylic acid functionalities. The azide can engage in reactions with alkynes, BCN, and DBCO through click chemistry methods to form stable triazole linkages. The amine group reacts readily with carboxylic acids, activated NHS esters, and carbonyls (including ketones and aldehydes).

Molecular Weight

581.7

Molecular Formula

C₂₄H₄₇N₅O₁₁

Functional Group 1

Acid

Functional Group 2

Azide

Functional Group 3

Amine

Reactive Group 1

Amine

Reactive Group 2

Alkyne

Reactive Group 3

Acid

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

In the field of drug delivery, it can be used to modify the surface of nanoparticles or liposomes. The azide group enables specific conjugation with targeting ligands or drugs through click chemistry, allowing for targeted and controlled release.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.