Description
Biotin-PEG11-azide is a monodisperse PEG biotinylation reagent designed for efficient click chemistry reactions with alkyne-containing molecules. Featuring a hydrophilic PEG spacer, it enhances the aqueous solubility of conjugated molecules, while minimizing steric hindrance during binding to avidin molecules.
Applications
Biotin-PEG11-azide finds widespread application in bioconjugation and labeling experiments, particularly those requiring site-specific and stable attachment of biotin to biomolecules. Its compatibility with click chemistry enables precise and selective biotinylation of proteins, peptides, and nucleic acids for various downstream applications, including affinity purification, immunoprecipitation, and fluorescence imaging.