Cat. No.: X24-03-YW0122
Azide/Biotin PEG reagent, Dde biotin-PEG4-azide, Purity 95%
Synonym: 1802907-93-2; Dde biotin-PEG4-azide; Dde biotin azide; AKOS040741615; BP-22678
- CAS Number: 1802907-93-2
- PubChem CID: 136663255
Properties
Description
Dde biotin-PEG4-azide is an effective reagent for incorporating a biotin moiety into alkyne-containing biomolecules through Cu(I)-catalyzed Click Chemistry. Its hydrophilic spacer arm enhances the solubility of labeled molecules in aqueous environments. The Dde protecting group enables the gentle release of biotinylated molecules from streptavidin under mild conditions using hydrazine.
Molecular Formula
C32H53N7O8S
Functional Group 2
Biotin
Identity
Confirmed by NMR.
Applications
Dde biotin-PEG4-azide is widely utilized in bioconjugation studies, protein labeling, and biomolecule immobilization. It enables specific and efficient biotinylation of alkyne-modified molecules, facilitating downstream applications such as affinity purification, protein detection, and cellular imaging. The hydrophilic spacer arm ensures optimal solubility of labeled molecules in aqueous solutions, while the Dde protecting group allows for controlled and mild release of biotinylated molecules from streptavidin, preserving the integrity of the target biomolecules.
For Research Use Only. Not For
Clinical Use.