Azide/Biotin PEG reagent, Dde biotin-PEG4-azide, Purity 95%

Synonym: 1802907-93-2; Dde biotin-PEG4-azide; Dde biotin azide; AKOS040741615; BP-22678

CAS Number: 1802907-93-2
PubChem CID: 136663255

Size

5 mg; 10 mg; 25 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Dde biotin-PEG4-azide is an effective reagent for incorporating a biotin moiety into alkyne-containing biomolecules through Cu(I)-catalyzed Click Chemistry. Its hydrophilic spacer arm enhances the solubility of labeled molecules in aqueous environments. The Dde protecting group enables the gentle release of biotinylated molecules from streptavidin under mild conditions using hydrazine.

Molecular Weight

695.9

Molecular Formula

C₃₂H₅₃N₇O₈S

Functional Group 1

Azide

Functional Group 2

Biotin

Functional Group 3

None

Form

Glass-like solid

Purity

95%

Identity

Confirmed by NMR.

Applications

Dde biotin-PEG4-azide is widely utilized in bioconjugation studies, protein labeling, and biomolecule immobilization. It enables specific and efficient biotinylation of alkyne-modified molecules, facilitating downstream applications such as affinity purification, protein detection, and cellular imaging. The hydrophilic spacer arm ensures optimal solubility of labeled molecules in aqueous solutions, while the Dde protecting group allows for controlled and mild release of biotinylated molecules from streptavidin, preserving the integrity of the target biomolecules.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.