Description
Azido-PEG1-CH2CO2H serves as a PEG linker featuring an azide group along with a terminal carboxylic acid. This azide moiety reacts readily with alkyne compounds such as BCN and DBCO through click chemistry processes. Furthermore, the terminal carboxylic acid can interact with primary amine groups when activated by agents like EDC or HATU to create stable amide bonds.
Applications
Azido-PEG1-CH2CO2H can be used in the modification of biomaterials to improve their biocompatibility and cell adhesion properties. In the synthesis of bioconjugates, it can provide a reactive site for coupling with other molecules. It is also valuable in the field of surface chemistry for creating functionalized surfaces with specific interactions. Additionally, it can be utilized in the development of hydrogels for controlled drug release.